Ointment of psoriasis - what is the ointment effective for the treatment of psoriasis?

Persons living with a diagnosis of "psoriasis", know first-hand how much depends on the right choice of medication. This disease does not forgive mistakes in treatments and neglect their health. An important role in the fight against the symptoms of psoriasis play intelligently chosen therapy external and timely started treatment. A key principle in the choice of a treatment regime, particularly in the early stages of development of psoriasis, is the principle of "do no harm" — the treatment should not strike a blow to the health of the skin, causing the appearance of adverse effects in the form of atrophy of the skin or of a withdrawal syndrome. In fact, the main task of the therapy — to extend the periods of rest and the health of the skin without the sudden and recurrence and aggravation.

ointment of psoriasis

Hormonal the ointment to the psoriasis: to treat or kill?

Common the group of outdoor facilities for the treatment of psoriasis are the ointment on the basis of certain hormones. These substances have the property to inhibit the activity of the immune system, reducing inflammation. Therefore, when the heavy acute exacerbations of psoriasis steroids routinely prescribed in the form of tablets or injections. However, this approach is fraught with serious side effects: therapy to change the background hormonal of the body, and the cancellation of the medication can lead to a dysfunction of the endocrine and cardiovascular systems.

Topical steroids (external hormone) in part deprived of their dangerous properties, the system of drugs based on hormones: the effect is manifested only in the application site. The advantage is the rapidity of the action: a few minutes after the application, patients notice a decrease in itching, and in the next few days, significantly reduced the redness in the area of psoriatic plaques, stops their growth and scaling.

But, unfortunately, the side effects are for topical steroids and is no less serious: because of the decrease of immunity in the area of the skin is refined and discoloration, the risk of joining a secondary infection. It is, without a doubt, which complicates the treatment. The most serious consequence of the application of topical steroids is the development of dependence. Other means (and themselves topical steroids) already cease to help, by causing alternate, sometimes stronger relapse after termination of medication. This is why sales topical steroids in Europe and the UNITED states without a prescription is prohibited. Autonomous and uncontrolled use of these funds belonging to the category of the powerful, is unacceptable.

It is important to know! Addison's disease — a condition that develops as a result of the long take glucocorticoid drugs. In response to hormonal treatment of adrenal glands stop yourself produce cortisol and other steroids, which is manifested by symptoms such as muscle weakness, loss of weight and appetite, decreased blood pressure, dehydration, heart palpitations and the constant feeling of alarm. In Addison's disease, the doctors are not always able to restore the function of the adrenal glands, the patients of life prescribe a hormone treatment.

Most of the remedies of topical steroids is not expensive and sold without a doctor's prescription, this is why cases of abuse of this type of treatment for psoriasis often face. Meanwhile, dermatologists do not recommend the use of steroids is extensive (more than 20% of the surface of the skin) places the destruction, as well as applying such means on the sensitive areas of the body — face, neck, skin folds, and the place of diaper rash. It is desirable, and does not renounce the idea to apply hormonal ointments and creams without a doctor's prescription: it is able to reduce the effect of the main treatment, harm to health and cause a heavy attack worsening of psoriasis.

The most often hormonal creams and ointments are made from the following substances:

  • betamethasone;
  • hydrocortisone;
  • mometasone;
  • methylprednisolone;
  • triamcinolone;

Traditional non hormonal cream for the treatment of psoriasis: the worst and the best?

Given the serious side-effects hormonal, creams and ointments, many patients prefer to treat psoriasis using less "aggressive" medication. Some of them are the prerogative of traditional medicine and the traditional recipes of skin treatment popular in the past.

The benefits of traditional treatment without hormones psoriasis should be attributed to his comparison with changes in means of security, renewable and the lack of serious side effects. Cons — different (often low) degree of efficiency and, in some cases, of allergic reactions, which develop in patients with any of the components or of the other.

the signs of psoriasis
  • Naftalan, Ichthyol, dermatological, an ointment-based pitch — have an anti-inflammatory and antiseptic. However, some of them you can't apply when the stages of psoriasis and on large surfaces of the defeat, while others (for example, tar ointment) have a certain effect, this is why it is not recommended to combine with phototherapy. In addition, the long-term use of these funds increases the probability of developing cancer of the skin. Traditional ointments also have a very strong odor and can stain clothing, and they are not very easy to use.
  • Menus for the substances possess anti-inflammatory and antimicrobial action, cause, reinforced by the exfoliation of dead skin cells, which speeds up the healing process of psoriatic plaques. Among the possible side effects of the action — the risk of inflammatory reactions, a burning sensation and pigmentation of the surrounding healthy skin (staining of healthy skin and hair brown).
  • Plant-based preparations (ointments and creams based on aloe, devjasil, celandine, sage, and other herbs have anti-inflammatory properties and healing actions, inhibit the development of skin infections. Aid in the treatment of psoriasis, complementing the effect of the main treatment.
  • Moisturizers (baby, creams, oils and cosmetics) are also complementary in the treatment of psoriasis, and help combat the dryness and tightening sensation of the skin. They are used in conjunction with medication to enhance the effect of the therapy.

Non-hormonal ointments and creams at the suggestion of a healing effect: it is clinically proven to

It is necessary to highlight the group of non-hormonal drugs, whose efficacy in the local treatment of psoriasis has been confirmed in clinical trials. On the other hand, ointments and creams in the previous group, the mechanism of action of these drugs is carefully studied. They have an undeniable advantage before hormonal means of communication with the highest level of security. However, and in the treatment of these tools, you must follow the application instructions and to learn about possible contra-indications.

  • Pimecrolimus has high activity. However, it is important to know that, in the case of bacterial or fungal lesions of the skin remedies on the basis of pimecrolimus, it is recommended that after the healing of the infection. When the uncontrolled use pimecrolimus can cause immune suppression local skin removal (local immunity), which increases the risk of adhesion to the secondary infection to the affected areas of the skin. Why the UNITED states, for example, the pimecrolimus is only recommended as the drug of the "second-line" treatment, there is only in the absence of the effect of all the other tools of the therapy. Pimecrolimus denied employment for children up to two years.
  • Of calcipotriol is a synthetic analogue of vitamin D3. Its action is based on the increase in the levels of calcium in the cells of the skin, which normalizes the rate of their division and promotes the resorption of psoriatic plaques. Because of calcipotriol is a tool (which, after a series of biochemical reactions is transformed into the active hormonal metabolite in the metabolism of calcium), there are a number of restrictions on its use. In particular, the calcipotriol does not apply in the case of more than 30% of the surface of the skin because of the risk of hypercalcemia. The latter may cause cardiac rhythm disorders and muscle cramps. Not it is also recommended to apply calcipotriol on sensitive areas of skin (face, neck, folds). Funds on the basis of this substance have an age limit. Of calcipotriol is not as suitable as an adjuvant in the case of the method of phototherapy treatment, because under the action of UV rays causes photosensitization and led to the development of a burn of the skin.
  • Pyrithione zinc. Thanks to proven the effectiveness and safety of treatments, medications for the treatment of psoriasis on the basis of this substance can be attributed to the category of "the environment." Zinc is a organic and natural remedy for the treatment of diseases of the skin. Its concentration in an epithelium of a human is approximately 20% of the total content in the body, and the rarity of this precious metal accompanied by a variety of lesions of the skin and degradation of wound healing. Drugs active zinc (pyrithione zinc) have a set of specific properties (anti-inflammatory, antibacterial, antifungal), to help reduce the itching of the skin, contribute to the development of the ceramides (lipids) to the skin, leading to the restoration of its barrier function. Tools pyrithione zinc activate so-called apoptosis (natural programmed death) pathologically modified cells of the skin and cells of inflammation, thus triggering the natural renewal of skin cells, reducing scaling and eliminating the psoriatic plaques. Studies have proven that the active zinc has comparable to hormonal means of effectiveness and a good safety profile, because it is virtually not absorbed at the surface of the skin, has no irritation and the action causing damage.

An ointment or a cream?

Many of these medications are available in the form of ointment and as a cream. How to choose the most appropriate form?

  • Ointments are more dense and oily, the texture, which allows a medicinal tool for a long time to find on the surface of the skin, especially if it is applied under a bandage.
  • The cream is soft texture, easy to apply and quickly absorbed, so that it can be applied, leaving the skin open, using no dressing, no fear of staining clothing or hands. Usually, the cream has a pleasant smell, which is also important during the daily use of the installation.
  • Unlike the ointment, cream, in a lesser extent has annoying action, and thus better suited for application on the face, bending the joint surface of the sensitive sites. Also the ointment is not suitable for the application on top of the cake moist patches of the skin with liquid removable. The cream in this sense is more versatile.
  • Traditionally, ointments of psoriasis are presented in more wide, but this imbalance is gradually aligned with the market appears more and more new pharmaceutical forms in the form of creams, gels, aerosol, easy-to-use, and is particularly suitable for application on difficult to access places (for example, on the scalp).
the treatment of psoriasis

Looking for a balance of price and quality

Try to compile the information received under the form of a table:

The group of the drug

The active substance

The action

The constraints and side effects

Hormonal creams and ointments

Betamethasone

The anti-inflammatory, anti-allergic (including antipruritic), and edematous. Hydrocortisone, methylprednisolone and other tools also have a particular action (overwhelming local immunity of the skin).

1. Not recommended to use long-term (more than 5 days). 2. Can lead to the development of local complications:

  • the discoloration and the violation of metabolic processes in the skin;
  • the withdrawal syndrome;
  • immunosuppressive action may result in the accession of a secondary infection on the skin.
  • Contraindicated in:
  • for the application on sensitive areas of skin (face, neck, folds);
  • in the case of large areas of the lesion (more than 30% of the skin).

Mometasone

Hydrocortisone

Glucocorticoids tool

Methylprednisolone

Triamcinolone

Non-hormonal traditional tools of

  • The oil
  • The sulphur
  • Ihtiolovaja
  • Fat
  • The tar

Have an anti-inflammatory and antiseptic.

  • Have quite low efficiency and do not affect the bacterial-fungal agents (at the time of accession of a secondary infection on the skin).
  • Uncomfortable for the application (are applied several times a day, often under the banner, require very long processing programs, to stain the linen, and have an unpleasant smell).
  • May cause irritation and dryness of the skin, as well as allergic reactions.

The substances causing active exfoliate the dead cells on the surface of the skin:

  • dithranol
  • the sulfur and salicylic acid

Cause reinforced exfoliate the dead skin cells, the anti-inflammatory and antimicrobial action.

Can cause an inflammatory reaction, a burning sensation and pigmentation of the surrounding healthy skin (staining of healthy skin and hair brown).

Non-drug

Pimecrolimus

Has the anti-inflammatory activity.

  • Do not use in the case of a bacterial or fungal lesions of the skin.
  • Can cause of the immune suppression local skin (reduction of local immunity).
  • Against-indicated in children under two years of age.

Of calcipotriol

Is a synthetic analogue of vitamin D3 contributes to the resorption of psoriatic plaques.

  • Is not recommended:
  • apply at the time of the defeat of more than 30% of the surface of the skin because of the risk of hypercalcemia;
  • apply on sensitive areas of skin (face, neck, folds of the skin of the head);
  • combine it with the method of phototherapy due to the risk of burning of the skin.
  • Contraindicated for patients under the age of six years.

Pyrithione zinc

Has a complex action:

  • anti-inflammatory;
  • antiprurigineux;
  • protection against infection;
  • the intensification of natural renewal of the cells of the epithelium to resolve the psoriatic plaques;
  • the restoration of the barrier function of the skin.
  • Has a security profile.
  • Has no restrictions on the duration of the application and of the place of the application.
  • Has no side effects (unless you're hypersensitive).
  • Is permitted to children up to one year.

Psoriasis is a chronic disease, therefore, in any patient, it is important to find a combination medication of high effectiveness and minimal side effects (and preferably an adequate price). And don't forget: before you start to use the tool, you read the instructions, all the counter-indications and side effects, and make sure that you consult your doctor. This will help you get the best possible result without harm to the health.

ointments against psoriasis

Timely begun treatment for psoriasis is a key factor of success. Don't forget that the sooner you begin to treat psoriasis, it is less likely that you will never have to resort to "heavy artillery" — hormonal means.